top of page

Science shows us the way

Send coherent and physiological information to the Central Nervous System to reprogram the neuromuscular signal and modulate the efferent response, normalize the muscle-fascial tone-trophism, the contractile capacity of the fibers and activate the related metabolic processes.


As we all know, through stimuli that come from outside and inside our body, a continuous flow of information is organized with our brain.
This information starts from the periphery and travels through receptors (mechanoreceptors, chemoreceptors, thermoreceptors), nerve fibers (peripheral nervous system), molecules and hormones.

Once arrived at the Central Nervous System (CNS), this information flow is processed and, instantly, response signals are transmitted.

The CNS therefore governs and regulates the osteo-tendon-muscular system through an input (afferent) and output (efference) communication network.

Today we know that the brain constantly uses this information and is able to change itself in relation to the stimuli it receives. This phenomenon is defined as Neuronal Plasticity. To obtain this plasticity, the stimulus must be ADEQUATE in terms of intensity, frequencies and amplitude. Each receptor is activated in relation to its specific stimulus which it transmits to the nerve ending, activating it without causing damage.

Pacinian corpuscles

Afferent and efferent signals

The Pacinian corpuscles are undoubtedly the mechanoreceptors most involved in vibrational perception. (Maximum activation sensitivity at 300 Hz, a frequency at which a pressure of 1 μm is sufficient to be activated).

Afferent signals come from external stimuli and send information to the central nervous system. Afferent neurons carry stimuli to the brain, via the spinal cord and thalamus. In this way, the signal is integrated and processed. The brain then coordinates a response through efferent signals that return to the rest of the body.

Efferent signals carry the message from the central nervous system to the muscles that activate the stimulus.

Screenshot 2024-04-01 at 17.06.25.png

- Type I exteroreceptors, are nerve endings covered by numerous layers of collagen lamellae that recognize external stimuli;
- Unimodal, they are activated exclusively by pressure;
- Phasic, they adapt quickly – They follow the all or nothing principle . Either they are activated or not.


Viss®: Science shows us the way

  • 1960 – Kandel and Rosenkranz : associate Mechanical Vibrations with the phenomena of LTC and LTP;

  • 1962 – Melzack and Wall : action of Vibration on pain control at 120 Hz;

  • 1975 – GE Lucier : The maximum activation of Alpha Motor Neurons occurs at a frequency of 300 Hz;

  • 1976 – (various authors) the Tonic Vibrational Reflex seems to operate predominantly, if not exclusively, through the Alpha motor neurons and does not use the same efferent cortical patterns used by voluntary movement;

  • 1980 – Wolpaw it is possible to produce plastic enhancements of the proprioceptive network using mechanical stimuli according to the LTC-LTP phenomena;

  • 1994 – Carmelo Bosco develops his vibrating platform;

  • 2000 – J. Rothwell and K. Rosenkranz : The vibrato muscle activates specific neuronal circuits, modifying the distribution of excitability of the brain circuits (this modulation continues even at the end of the stimulus);

  • 2003 – Rosenkranz : the effects of reprogramming of muscular capacity through the modulation of brain circuits are obtained only if the Mechanical Vibration is focal;

  • 2005 – Wolpaw JR : demonstrates the phenomena of LTC–LTP (Cellular Memory);

  • 2005 – Kandel: writes that new synapses are created in selected neural networks;

  • 2006 – L. Vecchiet and R. Saggin i: first clinical evidence on the effectiveness and duration of Square Wave Mechanical-Sound Vibration;

  • 2010 – Saggini et al.: demonstrates the effect of Focal Mechano-Sound Vibration on the Endocrine System and Muscle Fiber.

To produce a technology that uses:

The Mechano Acoustic
Square Wave  Vibration System


Recent research opens the way to a new interpretation of the functions of connective tissue, understood as a real "communicational network" within the model of mechano-sensitivity which considers cells as a sort of "metallic network", but not only . Today we know that, through specific membrane proteins (integrins), the connective system is able to interact with cellular mechanisms.
This theory refers to the concept of Tensegrity which is defined as the ability of a system to mechanically stabilize itself through tension and decompression forces that are distributed and balanced between each other.

Screenshot 2024-03-17 at 09.21.44.png
In this context, by means of specific membrane proteins such as integrins, the osteo-musculo-fascial system interacts with cellular mechanisms and mechanoreceptors using a more archaic, but certainly no less important, method of communication: the mechanical.. Through the transduction systems, by selecting specific endocrine and immune neuronal networks, the mechanical signal is transformed into an electrical and biochemical signal capable of regulating the responses of the Central Nervous System.

In this mechanical response model, capable of modulating peripheral and central nervous responses, ViSS® fits in thanks to its neuromodulation quality and allows the brain to regulate/become efficient by organizing the system
osteo-tendon-muscle more efficiently, better (Tensegrity).

bottom of page